Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV

Clinical Infectious Diseases

Abstract: New diagnostic tests and alternative samples to diagnose tuberculosis in children are needed to tackle the diagnostic gap of pediatric tuberculosis. The Determine TB LAM Ag test in urine demonstrated sensitivity of 15.9% and specificity of 90.6%. Collecting the urine in an adhesive bag was an independent risk factor for positivity (odds ratio, 11.38; P < .01).

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Gaps in TB-related knowledge and practices: An assessment of health care seeking behavior among adults with HIV & caregivers of paediatric patients with presumptive TB symptoms